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Frey syndrome is characterized by unilateral flushing and sweating of the facial skin innervated by the auriculotemporal nerve (neck, parotid region, and. A neurologist from Poland, Dr. Lucja Frey, provided a detailed assessment of the disorder and coined the term “auriculotemporal syndrome” in Auriculotemporal nerve syndrome, also known as Frey syndrome, is an uncommon clinical entity in children. It is widely thought to be the result.

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Periapical, mandibular and maxillary hard tissues — Bones of jaws Agnathia Alveolar osteitis Buccal exostosis Cherubism Idiopathic osteosclerosis Mandibular fracture Microgenia Micrognathia Intraosseous cysts Odontogenic: Oral and maxillofacial pathology K00—K06, K11—K14—, — These conditions include, but are not limited to, impaired thyroid function, pituitary abnormalities, allergies, metabolic diseases, auroculotemporal diseases, diabetes, menopause and a variety of tumors.

Rare Disease Database

Then, a starch powder such as corn starch is applied over the iodine solution. Orofacial soft tissues — Soft tissues around the mouth. Frey syndrome is due syndromme damage to these autonomic fibers. The other possible etiologic factors include parotitis, mandibular condylar fracture, blunt trauma, herpes zoster, associated central nervous system disorders such as syringomyelia, syndromee, and meningioma of the cerebellopontine angle tumor.

In very limited studies, there have been reports that abdominal fat implantation decreases the occurrence of Frey syndrome. Frey syndrome may occur in association with several neurologic disorders, such as syringomyelia, central nervous system tumors, and epilepsy.

Frey’s syndrome – Wikipedia

However, other studies have shown that the muscle flaps are ineffective at preventing the sequela of Frey syndrome. In managing symptomatic complaints of Frey syndrome, BTA injection, although not definitive aurriculotemporal, can significantly decrease the severity and thus morbidity of Frey syndrome.

This may occur consistently with every solid food feeding.

Hence children with Frey syndrome do not require treatment. Autologous and biosynthetic material have been used to create the physical barrier between the transected parotid and the overlying cutaneous tissues. Abdominal fat grafting Abdominal fat implantation to the parotidectomy defect is a commonly used technique for decreasing the postsurgical defect and improving auriculoyemporal. Le syndrome du nerf auriculo-temporal. Initial results have demonstrated that this therapy results in the suppression of sweating and causes no significant side effects.


Within the facial skin, the sweat glands are positioned at the same level or slightly deeper than the base of the ayndrome follicles.

Sternocleidomastoid muscle flap preventing Frey syndrome following parotidectomy. Views Read Edit View history.

Create a free personal account to access your subscriptions, sign up for alerts, and more. A Normal innervation of the parotid gland by the postganglionic parasympathetic nerve fibers from the auriculotemporal nerve. Individuals are then given an oral stimulus usually a highly acidic food such as a zyndrome wedge.

In extremely rare cases, Frey syndrome has been described in newborns, possibly following trauma due to delivery with forceps. Generalized hyperhidrosis can affect individuals of any age, race, gender or ethnic background.

Comparisons may be useful for a differential diagnosis. Although intraoperative techniques try to reduce severity and incidence of Frey syndrome, postoperative interventions have been focused on ameliorating symptoms once they develop.

In contrast to food allergy, Frey syndrome is usually unilateral, with a segmental distribution in the areas innervated by the auriculotemporal nerve. In children, the diagnosis is clinical. Basal cell adenoma Canalicular adenoma Ductal papilloma Monomorphic adenoma Myoepithelioma Oncocytoma Papillary cystadenoma lymphomatosum Pleomorphic adenoma Sebaceous adenoma Malignant: In affected individuals, discoloration usually purple due to excessive sweating occurs on the affected areas.

Link to citation list in Scopus. Complications of parotid surgery. In addition, ADM represents a suitable alternative to local fascia and muscle flaps for the prevention of Frey syndrome. More recent studies, which objectively measured flap thickness and assessed Frey syndrome by clinical symptoms as well as starch-iodine testing, have failed to demonstrate a reduction in the incidence of Frey syndrome with increased flap thickness. The temporoparietal fascia flap.

Treatment of postparotidectomy Frey syndrome with the interposition of temporalis fascia and sternocleidomastoid flaps. Reports of surgical transection of the auriculotemporal nerve, tympanic nerve, and greater auricular nerve have been described for the management of Frey syndrome, but they are not commonly practiced. Some of the current methods to prevent and treat symptomatic Frey syndrome are reviewed.

The previous sympathetic responses of sweating and flushing are now controlled by postganglionic parasympathetic fibers.

Teeth pulpdentinenamel. Botulinum toxin A in the treatment of patients with Frey syndrome. The barriers include 1.


Frey’s syndrome

Although the SCM auriculotemporaal is easy to harvest and can provide adequate cosmetic reconstruction, its ability to prevent Frey syndrome after parotidectomy is unclear.

Although the exact percentage is not agreed upon in the medical literature, some sources suggest that more than half of all individuals who undergo a parotidectomy eventually develop Frey syndrome. As a result of severance and inappropriate regeneration, the parasympathetic nerve fibers may switch course, resulting in “gustatory Sweating” or sweating syndroe the anticipation of eating, instead of the normal salivatory response.

Both patients were relieved permanently of this annoying syndrome by intracranial division of the glossopharyngeal nerve.

Frey Syndrome – NORD (National Organization for Rare Disorders)

Although this represents an effective technique for the prevention of Frey syndrome, it does require an extended incision, which can generally be hidden in the hairline. The sensory fibers innervate the auricle, external auditory meatus, tympanic membrane, temporomandibular joint, and the temporal scalp. Arch Otolaryngol Head Neck Surg.

For information about clinical trials conducted in Europe, contact: Similar to increasing the thickness of the elevated skin flap to shield the facial sweat glands from aberrant reinnervation, pedicled muscle and fascia flaps have been used to cover the resected parotid gland in an attempt to create a physical barrier between the overlying dermis and the transected nerve fibers within the parotid.

Recently, a cohort of 17 patients with postparotidectomy Frey syndrome who underwent both SCM and temporalis fascia transposition was reported by Dia and colleagues. Surgical treatment for Frey syndrome syndromee to medical management has been described, but clinical data to support its utilization are limited.

Another rarely auricuotemporal cause etiology of Frey syndrome is damage to the main sympathetic nerve chain in the neck. A An anatomic drawing of the superficial temporal artery and vein supplying the superficial temporal fascia demonstrating the proximity to the temporal branch of the facial nerve.

Because of this, any gustatory stimulus produces erythema and sweating instead of salivation.